Chemotherapy-induced neutropenia and febrile neutropenia in patients with gynecologic malignancy
نویسندگان
چکیده
منابع مشابه
Chemotherapy-induced neutropenia and febrile neutropenia in patients with gynecologic malignancy
Chemotherapy-induced neutropenia is a common complication in cancer treatment. In this study, we investigated chemotherapy-induced neutropenia that was recently detected in all patients with gynecologic malignancy. Between January 2009 and December 2011, we examined cases of chemotherapy-induced neutropenia reported in our hospital. We analyzed the incidence and clinical features of chemotherap...
متن کاملChemotherapy induced febrile neutropenia: management and prevention.
chemotherapy remains the cornerstone of cancer therapy. In most cases bone marrow suppression represents the doselimiting toxicity of these drugs. Druginduced DNA damage at the level of bone marrow progenitor cells results in a fall in circulating neutrophil count. Patients with neutropenia are at increased risk of infection and sepsis.1 The timing of neutropenia is generally predictable; it ty...
متن کاملFebrile neutropenia in chemotherapy treated small-cell lung cancer patients
BACKGROUND Chemotherapy with platinum agent and etoposide for small-cell lung cancer (SCLC) is supposed to be associated with intermediate risk (10-20%) of febrile neutropenia. Primary prophylaxis with granulocyte colony-stimulating factors (G-CSFs) is not routinely recommended by the treatment guidelines. However, in clinical practice febrile neutropenia is often observed with standard etoposi...
متن کاملIncidence and Impact of Baseline Electrolyte Abnormalities in Patients Admitted with Chemotherapy Induced Febrile Neutropenia
BACKGROUND Febrile neutropenia (FN) and myelosupression remain a challenging oncologic medical emergency and dose limiting toxicity associated with chemotherapy for cancers. Various factors are known to affect the outcomes for patients diagnosed with FN. Electrolyte abnormalities have commonly been observed, but the real incidence and their impact has been only scarcely studied in literature. ...
متن کاملOutcomes in 102 patients that present to the emergency department with chemotherapy-induced febrile neutropenia.
OBJECTIVE Febrile neutropenia (FN) is a major toxic responseto chemotherapy requiring prompt medical attention. There are a limited number of reports on clinical outcome in patients with FN that present to emergency departments. METHODS We retrospectively evaluated clinical manifestations, therapeutic outcomes, and risk factors for FN in 102 adult patients that presented to the emergency depa...
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ژورنال
عنوان ژورنال: Anti-Cancer Drugs
سال: 2015
ISSN: 0959-4973
DOI: 10.1097/cad.0000000000000279